Nigeria is believed to host the largest population of the poor in the West Africa Sub region. To this end federal, state and local governments have developed poverty eradication policies yet not much has been achieved. Among them is the establishment of microfinance institutions expected to provide credits for small and medium scale enterprises that could not fulfill the requirement of commercial banks for facilities. Intervention of microfinance banks in poverty alleviation in Nigeria needs to be appraised. This study examined poverty alleviation as a function of loan acquisition, understanding the concept by operators, determinants of standard practices and loan repayment. Exploratory cross sectional research design was adopted. The population consisted of 53 microfinance banks and 4016 beneficiaries in Ogun State, Nigeria. Stratified random sampling techniques were used to select ten (10) microfinance banks in Ogun State whose operation spans from 2008-2012. Sample size of 2000 was arrived at using Yaro Yemane Formula. Structured questionnaire titled ‘Microfinance Banking and Poverty Alleviation’ (MIBPOVA) on a six- point Likert scale were used and the response rate was 89.5%.