Rice occupies enviable prime place among food crops cultivated around the world especially Asian countries. The exploitation of hybrid vigour is a commercially viable option for enhancing productivity & production of rice.The monograph provides comprehensive information on hybrid rice making and its genetic analysis. This monograph also covers Evaluation and selection of parental lines for hybrid making by genetic and molecular divergence;Procedure of hybrid making ;Evaluation of hybrids in terms of heterosis, specific combining ability ;Nicking ability of parents;Phenotypic stability of F1 hybrids across locations;Prediction of heterosis through molecular markers. This Monograph informs and updates the necessity of hybrid rice, materials and methods of hybrid making; reviews the literature available world wide right from selection of parents, estimation of gca of parents, sca and heterosis of hybrids till successful release of hybrid for commercial cultivation. We hope that this book would be useful to students, teachers and researchers engaged in the rice breeding and serve as a practical book for university P.G and Ph.D scholars and infant researchers working on hybrid rice.